Monocytes and macrophages synthesize and secrete thrombospondin
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چکیده
منابع مشابه
Monocytes and macrophages synthesize and secrete thrombospondin.
Thrombospondin, one of the major glycoproteins released from alpha-granules of thrombin-stimulated platelets, is a disulfide-linked trimer of 160,000-dalton subunits. Cultured human monocytes secreted thrombospondin (determined by an enzyme-linked immunosorbent assay) into the culture medium in a time-dependent manner (1.45 micrograms/10(6) cells/24 hr); secretion was totally blocked by cyclohe...
متن کاملMonocytes and Macrophages Synthesize and Secrete
Thrombospondin, one of the major glycoproteins released from a-granules of thrombin-stimulated platelets, is a disulfide-linked trimer of 1 60,000-dalton subunits. Cultured human monocytes secreted thrombospondin (determined by an enzyme-linked immunosorbent assay) into the culture medium in a time-dependent manner (1 .45 g/10’ cells/24 hr); secretion was totally blocked by cycloheximide (1 g/m...
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alpha2-Macroglobulin levels in the supernates of cultures of different subpopulations of human peripheral blood mononuclear leukocytes were assayed by a radioimmunoassay. Unfractionated mononuclear leukocytes produced greater amounts of the macroglobulin (4.0 vs. 0.8 ng/10(6) cells) than did subpopulations enriched in T or B+T lymphocytes, by passage through nylon wool or cotton wool columns, r...
متن کاملCultured human fibroblasts synthesize and secrete thrombospondin and incorporate it into extracellular matrix.
Thrombospondin, a major glycoprotein released from alpha granules of thrombin-stimulated platelets, is a disulfide-bonded trimer of 160-kilodalton subunits. Cultured human foreskin and fetal lung fibroblasts secreted thrombospondin (determined by enzyme-linked immunosorbent assay) into the culture medium in a time-dependent manner (15.7 and 5.8 micrograms per 10(6) cells per 24 hr, respectively...
متن کاملresistance training, interleukin-10, lymphocytes, monocytes, macrophages.
مقدمه: پرفشارخونی یکی از بیماریهای همراه با بیماری دیابت نوع 2 است که در بیشتر بیماران دیابتی نوع 2 دیده می‌شود. هدف از انجام این تحقیق بررسی اثر ورزش ایروبیک بر روی فشارخون زنان دیابتی نوع 2 است. روش پژوهش: تعداد 32 بیمار دیابتی نوع 2 که دارای فشارخون بالا بودند به صورت تصادفی به دو گروه تقسیم شدند: گروه ورزش ایروبیک (16 نفر) و گروه کنترل (بدون ورزش) (16 نفر)...
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ژورنال
عنوان ژورنال: Blood
سال: 1985
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v65.1.79.bloodjournal65179